pentobarbital will minimize the level or impact of conjugated estrogens by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lessen the level or impact of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
With therapeutic doses of TCAs, barbiturates maximize metabolism and decrease blood concentrations of TCAs.
Warning when discontinuing CYP3A4 inducers that are coadministered with benzhydrocodone (prodrug of hydrocodone); plasma concentrations of hydrocodone may improve and may end up in likely fatal respiratory depression.
pentobarbital will decrease the extent or impact of fosphenytoin by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Keep track of.
pentobarbital will lower the extent or impact of tipranavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will decrease the level or result of oxybutynin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unknown.
pentobarbital will lessen the level or result of cilostazol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital decreases amounts of toremifene by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. CYP3A4 inducers maximize amount of toremifene metabolism, reducing more info the regular-point out focus in serum.
With therapeutic doses of TCAs, barbiturates enhance metabolism and decrease blood concentrations of TCAs.
pentobarbital will lessen the level or influence of tinidazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will minimize the extent or effect of fludrocortisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Premature infants are notably vulnerable to the depressant effects of barbiturates; if barbiturates are made use of for the duration of labor and supply, resuscitation machines ought to be available
pentobarbital will lessen the level or outcome of voriconazole by influencing hepatic enzyme CYP2C9/ten metabolism. Minimal/Significance Unfamiliar.